Valnir tablets – Information, specialists, frequent questions.

Usage of Valnir tablets

This leaflet answers some common questions about VALNIR.

It does not contain all of the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have benefits and risks. Your doctor has weighed the risks of you taking VALNIR against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, talk to your doctor or pharmacist.

Keep this leaflet with your medicine. You may need to read it again.

VALNIR is used to prevent cytomegalovirus (CMV) infection and disease following solid organ transplantation.

VALNIR belongs to a group of medicines called antivirals. It works by stopping the production of CMV, preventing infection. VALNIR also prevents herpes simplex infections.

CMV is another type of herpes virus. It can cause symptoms similar to glandular fever.

Your doctor may have prescribed VALNIR for another reason. Ask your doctor if you have any questions about why VALNIR has been prescribed for you.

VALNIR is not recommended for use in children, as there have been no studies of its effects in children.

VALNIR is available only with a doctor’s prescription.

There is no evidence that VALNIR is addictive.

Special precautions

When you must not take it

Do not take VALNIR if you are allergic to medicines containing valaciclovir, aciclovir or any of the ingredients listed at the end of this leaflet. Some of the symptoms of an allergic reaction may include skin rash, itching or hives, swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing, wheezing or shortness of breath or fainting.

Do not take VALNIR if the expiry date (Exp.) printed on the pack has passed.

Do not take VALNIR if the packaging is torn or shows signs of tampering.

Before you start to take it

Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives.

Tell your doctor if you are pregnant or plan to become pregnant. Your doctor will discuss the risks and benefits of taking VALNIR during pregnancy.

Tell your doctor if you are breastfeeding or wish to breastfeed. Your doctor will discuss the risks and benefits of taking VALNIR when breastfeeding.

Tell your doctor if you have, or have had, any medical conditions, especially the following:

  • anaemia
  • a kidney or liver condition

If you have not told your doctor about any of the above, tell them before you start taking VALNIR.

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop.

Some medicines may be affected by VALNIR, or may affect how well it works. These include:

  • mycophenolate mofetil
  • cyclosporin
  • tacrolimus

These medicines are commonly taken by transplant patients and require close attention.

Your doctor can tell you what to do if you are taking any of these medicines.

If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist.

Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking VALNIR.

How much to take

The dose varies from patient to patient.

The usual dose is four 500 mg tablets (2 grams) four times a day for ninety days.

Patients with kidney disease may need a reduced dose.

Follow all directions given to you by your doctor and pharmacist carefully.

How to take VALNIR

Swallow the tablets with a glass of water.

For the prevention of CMV infection, VALNIR must be taken four times a day (morning, noon, afternoon and evening).

If you forget to take VALNIR

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take the missed dose as soon as you remember, and then go back to taking your tablets as you would normally.

Do not take a double dose to make up for the dose you missed.

If you are not sure what to do, ask your doctor or pharmacist.

How long to take VALNIR for

Keep taking VALNIR for as long as your doctor recommends. VALNIR is usually taken for 90 days.

If you take too much VALNIR (overdose)

Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much VALNIR. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.

Things you must do

Before starting any new medicine, tell your doctor or pharmacist that you are taking VALNIR.

Tell all the doctors, dentists and pharmacists who are treating you that you are taking VALNIR.

If you become pregnant or are trying to become pregnant or intend to breastfeed while you are taking VALNIR, tell your doctor.

Visit your doctor regularly so they can check on your progress.

Drink plenty of fluids while you are taking VALNIR.

Things you must not do

Do not use VALNIR to treat any other conditions unless your doctor tells you to.

Do not give VALNIR to anyone else, even if they have the same condition as you.

Do not stop taking VALNIR tablets, or alter the dose, without first checking with your doctor.

Things to be careful of

Be careful driving or operating machinery until you know how VALNIR affects you. VALNIR does not normally affect alertness; however make sure you know how VALNIR affects you before driving, operating machinery or anything else that could be dangerous.


Keep VALNIR where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Keep your tablets in their pack until it is time to take them. If you take the tablets out of their pack they may not keep well.

Keep your tablets in a cool dry place where the temperature stays below 25°C.

Do not store VALNIR or any other medicine in the bathroom or near a sink.

Do not leave VALNIR in the car or on window sills. Heat and dampness can destroy some medicines.


If your doctor tells you to stop taking VALNIR, or your tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Adverse and side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking VALNIR.

Like all other medicines, VALNIR may have unwanted side effects in some people. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

Do not be alarmed by this list of possible side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if you notice any of the following and they worry you:

  • headache
  • gastrointestinal discomfort such as vomiting, nausea, diarrhoea, constipation, abdominal pain and indigestion.

Tell your doctor if you notice any of the following side effects which are more common in patients with kidney disease or those taking high doses of VALNIR:

  • hallucinations
  • confusion
  • dizziness
  • drowsiness

Allergic reactions to VALNIR are rare. However, if you think you are having an allergic reaction, tell your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following:

  • wheezing
  • swelling of the lips or mouth
  • difficulty in breathing
  • hay fever
  • lumpy rash
  • fainting

Rare side effects of VALNIR include unusual bruising or bleeding

Tell your doctor immediately if you notice any bruising or bleeding, as this may indicate that your blood is not clotting properly.

  • sensitivity to UV light, such as development of a rash like sunburn even after short exposure to UV light. Talk to your doctor or pharmacist if you experience this
  • kidney problems, which get better when VALNIR treatment is stopped
  • liver problems, which get better when VALNIR treatment is stopped.

Other side effects not listed above may also occur in some patients. Tell your doctor if you notice anything that is making you feel unwell.

Questions about Valnir tablets

Our experts have answered 3 questions about Valnir tablets

There is no reliable information on the use of valaciclovir (Valnir) in pregnancy. It should be taken only if the potential benefit outweighs the potential risk
2 answers

The dose depends on the reason for treatment. Dosages and duration of treatment for herpes zoster (shingles), hepres simplex (cold sore) and genital herpes are different
1 answers

Prof. Johan Rosman
Prof. Johan Rosman
This drug has a dose reduction recommendation in renal failure. A problem with that is that dialysis removes a lot of the drug, so the producer of the drug recommends to give 1000 mg per day…
1 answers

What professionals prescribe Valnir tablets?

All the contents published in, especially medical question and answers, are informative and in no case must be considered a substitute for medical advice.