Sozol tablets – Information, specialists, frequent questions.

Usage of Sozol tablets

This leaflet answers some common questions about SOZOL. It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking SOZOL against the benefits this medicine is expected to have for you.

Use SOZOL as directed and follow the advice given in the leaflet.

If you have any concerns about taking this Medicine, ask your doctor or pharmacist.

Keep this leaflet with the medicine. You may need to read it again.

The name of your medicine is SOZOL. It contains the active ingredient called pantoprazole.


SOZOL is used to treat and help heal duodenal and gastric ulcers.

Depending on the position of the ulcer it is called a gastric or duodenal ulcer. A gastric ulcer occurs in the stomach. A duodenal ulcer occurs in the duodenum which is the tube leading out of the stomach

These can be caused in part by too much acid being made in the stomach. Most people who have a peptic ulcer also have bacteria called Helicobacter pylori in their stomach.

When SOZOL is taken with antibiotics the combination therapy will kill the Helicobacter pylori and let your ulcer heal.

Reflux disease

SOZOL is also used to treat reflux oesophagitis or reflux disease. This can be caused by “washing back” (reflux) of food and acid from the stomach into the food pipe, also known as the oesophagus.

Reflux can cause a burning sensation in the chest rising up to the throat, also known as heartburn.

SOZOL is also used to prevent reflux oesophagitis from coming back.

Zollinger-Ellison syndrome

SOZOL is used to treat a rare condition called Zollinger-Ellison syndrome, where the stomach produces very large amounts of acid, much more than in ulcers and reflux disease.

Other uses

Your doctor may have prescribed SOZOL for another reason. Ask your doctor if you have any questions about why SOZOL has been prescribed for you.

How SOZOL works

SOZOL belongs to a group of medicines called proton pump inhibitors (PPIs).

SOZOL works by decreasing the amount of acid the stomach makes to give relief from the symptoms and allow healing to take place.

There is no evidence that SOZOL is addictive.

This medicine is available only with a doctor’s prescription.

Special precautions

When you must not take it

Do not take SOZOL if:

  1. You have an allergy to:
  • pantoprazole
  • any of the ingredients listed at the end of this leaflet.

Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing.

  1. You have severe liver disease or cirrhosis

Do not take SOZOL if the packaging is torn or shows signs of tampering.

Do not take SOZOL after the expiry date (EXP) printed on the pack has passed.

Do not take SOZOL in combination with antibiotics or any other medicine if:

  • you are allergic to any of the antibiotics or medicines your doctor may prescribe with SOZOL.
  • you have moderate to severe liver or kidney disease.

Do not take SOZOL in combination with atazanavir (an anti-viral medication).

SOZOL should not be given to children. Safety and effectiveness of SOZOL in children have not been established.

If you are not sure whether you should start taking SOZOL alone, or SOZOL in combination with antibiotics, talk to your doctor.

Before you start to take it

You must tell your doctor if:

  1. You have any allergies to:
  • pantoprazole
  • any of the ingredients listed at the end of this leaflet
  • any other medicines, or any other substances, such as foods, preservatives or dyes.
  1. You are pregnant, intend to become pregnant, are breastfeeding or intend to breastfeed.
Your doctor will discuss the risks and benefits of taking SOZOL during pregnancy or while breast-feeding.
  1. You have or have had any other medical conditions.

If you have not told your doctor about any of the above, tell them before you take SOZOL.

Taking other medicines

Tell your doctor if you are taking any other medicines, including medicines that you buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines may be affected by SOZOL, or may affect how well it works. These may include medicines used to prevent blood clots (anticoagulants) and medicines whose activity depend on the acidity of the stomach e.g. ketoconazole.

You may need different amounts of your medicine, or you may need to take different medicines. Your doctor will advise you.

How much to take

The usual dose is one tablet per day.

However, if your doctor also prescribes antibiotics in combination with SOZOL for the treatment of duodenal ulcers, the dose of SOZOL is two tablets per day. The first tablet should be taken in the morning and the second tablet should be taken before the evening meal for 7 days.

Your doctor will prescribe the dose that is right for you.

The dose and frequency of SOZOL that your doctor prescribes for you depends on your medical condition.

Your doctor may change the dose as your condition changes.

How and when to take it

Swallow your tablets whole with a little water with or without food.

If you are taking other medicines, like antibiotics, in combination with SOZOL therapy, follow the instructions for the use of each medicine carefully.

Do not crush or chew the tablets. SOZOL tablets have a special coating to protect them from the acidic contents of your stomach. For SOZOL to work effectively, this coating must not be broken.

How long to take it

Your doctor will tell you how long to take your tablets.

If you forget to take it

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise, take it as soon as you remember, and then go back to taking it as you would normally.

Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.

If you have trouble remembering to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)

Immediately telephone your doctor or Poisons Information Centre (13  11  26). or go to Accident and Emergency at your nearest hospital, if you think that you or anyone else may have taken too much PANTOP. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Keep telephone numbers for these places handy.

Things you must do

Use SOZOL exactly as your doctor has prescribed.

Tell your doctor immediately if you become pregnant while you are taking SOZOL.

Tell all doctors, dentists and pharmacists who are treating you that you are taking SOZOL.

If you take SOZOL for a long period of time, e.g. over 1 year, you will need to see your doctor regularly so that he/she can monitor your condition.

Tell your doctor if you do not feel better while taking SOZOL. Your doctor may recommend further examination.

Things you must not do

Do not give SOZOL to anyone else, even if they have the same symptoms as you.

Do not use SOZOL to treat any other complaints unless your doctor tells you to.

Things that may help your condition

Some self help measures suggested below may help your condition. Talk to your doctor or pharmacist about these measures and for more information.

  • Alcohol – your doctor may advise you to limit your alcohol intake.
  • Aspirin and many other medicines used to treat arthritis, period pain, headaches – These medicines may irritate the stomach and may make your condition worse. Your doctor or pharmacist may suggest other medicines you can take.
  • Caffeine – your doctor may advise you to limit the number of drinks which contain caffeine, such as coffee, tea, cocoa and cola drinks, because they contain ingredients that may irritate your stomach.
  • Eating habits – eat smaller, more frequent meals. Eat slowly and chew your food carefully. Try not to rush at meal times.
  • Smoking – your doctor may advise you to stop smoking or at least cut down.
  • Weight – your doctor may suggest losing some weight to help your condition.


Keep your tablets in their blister pack until it is time to take them.

If you take the tablets out of the blister pack they may not keep well.

Keep SOZOL tablets in a cool dry place where the temperature stays below 25°C.

Do not store SOZOL or any other medicines in a bathroom or near a sink.

Do not leave it in the car or on window sills. Heat and dampness can destroy some medicines.

Keep SOZOL where children cannot reach it. A locked cupboard at least one-and a- half metres above the ground, is a good place to store medicines.


If your doctor tells you to stop taking SOZOL or the tablets have passed their expiry date, ask your pharmacist what to do with any tablets that are left over.

Adverse and side effects

Tell your doctor as soon as possible if you have any problems while taking SOZOL, even if you do not think the problems are connected with the medicine or they are not listed in this leaflet.

Like other medicines, SOZOL can cause some side effects. If they occur, most are likely to be minor and temporary. However, some may be serious and need medical attention.

Ask your doctor or pharmacist any questions you may have.

Tell your doctor if you notice any of the following and they worry you:

  • headache
  • dizziness
  • diarrhoea
  • nausea or vomiting
  • stomach pain
  • excessive gas in the stomach or bowel
  • indigestion
  • constipation
  • dry mouth
  • metallic taste
  • weakness or tiredness
  • increased sweating
  • blurred vision
  • skin problems such as itchiness and rash

These are the more common side effects of SOZOL. Some of these side effects may be due to the combination of other medicines you are taking with SOZOL.

Tell your doctor immediately if you notice any of the following:

  • unusual tiredness or weakness
  • nausea, vomiting, loss of appetite, feeling generally unwell, fever, itching, yellowing of the skin and eyes, and dark coloured urine.
  • skin problems such as itchiness and rash, or swelling, blistering or peeling of the skin.
  • swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing.
  • frequent infections such as fever, severe chills, sore throat or mouth ulcers
  • chest pain
  • shortness of breath
  • high blood pressure
  • swelling of the legs
  • bleeding or bruising more easily than normal
  • depression, confusion or anxiety

These may be serious side effects and you may need urgent medical attention.

Serious side effects are rare.

Other side effects not listed above may occur in some people. Tell your doctor if you notice anything that is making you feel unwell when you are taking, or soon after you have finished taking, SOZOL.

Ask your doctor or pharmacist if you do not understand some of the information in this list. Do not be alarmed by this list of possible side effects. You may not experience any of them.

Questions about Sozol tablets

Our experts have answered 3 questions about Sozol tablets

 Guang Chen
Guang Chen
Sozol or pantoprazole is a member of the proton pump inhibitor family. It suppresses stomach acid. We typically use it to treat reflux or peptic ulcer disease.
1 answers

 Tom Zhou
Tom Zhou
For short term you can.
However if your reflux is still bad despite taking Sozol 40mg ONCE a day, then you should see your doctor.

A gastroscopy and other investigations…
1 answers

Prof. Johan Rosman
Prof. Johan Rosman
In my patients I see around 3 times per year that they come to hospital because their kidney function goes off the rails after taking this drugs. We should realize however that there are an enormous…
1 answers

What professionals prescribe Sozol tablets?

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