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Dr. Joseph Jabbour
Dr. Joseph Jabbour

Hi there,

Clonac is Diclofenac which is a non-steroidal anti inflammatory. You can certainly take this in combination to paracetamol and codeine.
The combination of these medications can help alleviate the pain you may have, but it is always important that the pain is investigated thoroughly and managed if possible.
With any non-steroidal anti inflammatory, it's important to take with food as it can upset your stomach and may cause stomach ulcers.

All the best.

Dr. Geoffrey Boyce
Dr. Geoffrey Boyce

Probably nothing . The base compound levodopa has a half life of 60-90 mins. Both Madopar and Sinemet increase that to 120-150 mins. Stalevo further increases the active life to about 180-200mins.

Hence the need in advanced PD to need Duodopa, Apomorphine or Deep Brain Stimulation.

Madopar 62.5mg is the lowest dose of Madopar, and usually used in the starting phase of treatment.